Cathepsin K Antibody / CTSK

Biorbyt

Cathepsin K Antibody / CTSK

10

Optimal dilution of the Cathepsin K antibody to be determined by the researcher.1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1) IHC-P

Research Use Only

Monoclonal

CTSK/2791

Unconjugated

CTSK

cathepsin K

CTS02, CTSO, CTSO1, CTSO2, PKND, PYCD, cathepsin K, cathepsin O, cathepsin O1, cathepsin O2, cathepsin X

Mouse

IgG1

Cathepsin K

The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature.

Human

-20°C,2°C to 8°C

12352203