Cathepsin L antibody [33/2]

GeneTex

Cathepsin L antibody [33/2]

9

WB: 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen

Research Use Only

Monoclonal

33/2

Unconjugated

CTSL

cathepsin L

CATL, CTSL1, MEP, procathepsin L, cathepsin L1, major excreted protein

Mouse

IgG1

Cathepsin L1

Cathepsins are lysosomal proteases that play an important role in the intracellular degradation of exogenous and endogenous proteins, activation of enzyme precursors, and tumor invasion and metastasis. Normally located in lysosomes of almost all mammalian cells, they can be secreted from the cell under certain conditions. Cathepsin L is responsible for most of the intra-lysosomal breakdown of normal cells. Cathepsin L is secreted by numerous transformed cells in its inactive pro-form, and mRNA expression level seems to correlate with their metastatic potential.

-20°C or -80°C,2°C to 8°C

12352203