CBX1 / HP1 beta antibody
GTX106418
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetCBX1
Overview
- SupplierGeneTex
- Product NameCBX1 / HP1 beta antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID10951
- Target nameCBX1
- Target descriptionchromobox 1
- Target synonymsCBX; chromobox homolog 1 (HP1 beta homolog Drosophila ); chromobox protein homolog 1; heterochromatin protein 1 homolog beta; heterochromatin protein 1-beta; heterochromatin protein p25 beta; HP1 beta homolog; HP1-BETA; HP1Hsbeta; HP1Hs-beta; M31; MOD1; modifier 1 protein; p25beta
- HostRabbit
- IsotypeIgG
- Protein IDP83916
- Protein NameChromobox protein homolog 1
- Scientific DescriptionThis gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Ensuring meiotic DNA break formation in the mouse pseudoautosomal region. Acquaviva L et al., 2020 Jun, NatureRead more
- Histone H1 acetylation at lysine 85 regulates chromatin condensation and genome stability upon DNA damage. Li Y et al., 2018 Sep 6, Nucleic Acids ResRead more
- Contrasting behavior of heterochromatic and euchromatic chromosome portions and pericentric genome separation in pre-bouquet spermatocytes of hybrid mice. Scherthan H et al., 2014 Dec, ChromosomaRead more