CCR5 antibody [N1N2], N-term

GeneTex

CCR5 antibody [N1N2], N-term

9

ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

CCR5

C-C motif chemokine receptor 5

C-C chemokine receptor type 5; C-C motif chemokine receptor 5 A159A; CCCKR5; CC-CKR-5; CCR-5; CD195; chemokine (C-C motif) receptor 5; chemokine receptor CCR5; chemokine recptor CCR5 Delta32; chemr13; CKR5; CKR-5; CMKBR5; HIV-1 fusion coreceptor; IDDM22; mutant C-C motif chemokine receptor

Rabbit

IgG

This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]

Human

2°C to 8°C,-20°C or -80°C

12352203