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CD11b antibody [M1/70]

Research Use Only
GTX00608
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Neutralisation/Blocking, Other Application
Product group Antibodies
ReactivityHuman, Monkey, Mouse, Primate, Rabbit
TargetItgam
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    CD11b antibody [M1/70]
  • Delivery Days Customer
    9
  • Applications
    Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Neutralisation/Blocking, Other Application
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    M1/70
  • Concentration
    0.5 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID16409
  • Target name
    Itgam
  • Target description
    integrin alpha M
  • Target synonyms
    CD11 antigen-like family member B; Cd11b; CD11B (p170); CD11b/CD18; cell surface glycoprotein MAC-1 alpha subunit; cell surface glycoprotein MAC-1 subunit alpha; complement receptor type 3; CR; CR3; CR-3 alpha chain; CR3A; F730045J24Rik; integrin alpha-M; leukocyte adhesion receptor MO1; Ly-4; Ly-40; Mac-; MAC1; Mac-1; Mac-1 alpha; Mac-1a; macrophage antigen alpha
  • Host
    Rat
  • Isotype
    IgG2b
  • Reactivity
    Human, Monkey, Mouse, Primate, Rabbit
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Endothelial cell-derived CD95 ligand serves as a chemokine in induction of neutrophil slow rolling and adhesion. Gao L et al., 2016 Oct 20, Elife
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  • Distinct roles for talin-1 and kindlin-3 in LFA-1 extension and affinity regulation. Lefort CT et al., 2012 May 3, Blood
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  • Monocyte heterogeneity underlying phenotypic changes in monocytes according to SIV disease stage. Kim WK et al., 2010 Apr, J Leukoc Biol
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  • Inhibition of vascular endothelial growth factor reduces angiogenesis and modulates immune cell infiltration of orthotopic breast cancer xenografts. Roland CL et al., 2009 Jul, Mol Cancer Ther
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  • Early rise in inflammation and microcirculatory disorder determine the development of autoimmune pancreatitis in the MRL/Mp-mouse. Sorg H et al., 2008 Dec, Am J Physiol Gastrointest Liver Physiol
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  • Deficiency of decay-accelerating factor and complement receptor 1-related gene/protein y on murine platelets leads to complement-dependent clearance by the macrophage phagocytic receptor CRIg. Kim DD et al., 2008 Aug 15, Blood
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  • Regulation of immune response and inflammatory reactions against viral infection by VCAM-1. Ou R et al., 2008 Mar, J Virol
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  • Lyn-coupled LacCer-enriched lipid rafts are required for CD11b/CD18-mediated neutrophil phagocytosis of nonopsonized microorganisms. Nakayama H et al., 2008 Mar, J Leukoc Biol
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  • Dynamic regulation of PU.1 expression in multipotent hematopoietic progenitors. Nutt SL et al., 2005 Jan 17, J Exp Med
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  • A mAb to the beta2-leukocyte integrin Mac-1 (CD11b/CD18) reduces intimal thickening after angioplasty or stent implantation in rabbits. Rogers C et al., 1998 Aug 18, Proc Natl Acad Sci U S A
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