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CD11b antibody [M1/70]

Name: CD11b antibody [M1/70]
SKU: GTX00608_G10
Availability: BackOrder

GTX00608

ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Neutralisation/Blocking, Other Application

Product group Antibodies

ReactivityHuman, Monkey, Mouse, Primate, Rabbit

TargetItgam

Overview

Supplier
GeneTex
Product Name
CD11b antibody [M1/70]
Delivery Days Customer
9
Applications
Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Neutralisation/Blocking, Other Application
Certification
Research Use Only
Clonality
Monoclonal
Clone ID
M1/70
Concentration
0.5 mg/ml
Conjugate
Unconjugated
Gene ID16409
Target name
Itgam
Target description
integrin alpha M
Target synonyms
CD11b/CD18, CR3, CR3A, Cd11b, F730045J24Rik, Ly-40, MAC1, Mac-1, Mac-1a, integrin alpha-M, CD11 antigen-like family member B, CD11B (p170), CR-3 alpha chain, Mac-1 alpha, cell surface glycoprotein MAC-1 alpha subunit, cell surface glycoprotein MAC-1 subunit alpha, complement receptor type 3, leukocyte adhesion receptor MO1, macrophage antigen alpha
Host
Rat
Isotype
IgG2b
Reactivity
Human, Monkey, Mouse, Primate, Rabbit
Storage Instruction
2°C to 8°C
UNSPSC
12352203

References

Gao L, Gülcüler GS, Golbach L, et al. Endothelial cell-derived CD95 ligand serves as a chemokine in induction of neutrophil slow rolling and adhesion. Elife. 2016,5:pii: e18542. doi: 10.7554/eLife.18542.
Read this paper
Lefort CT, Rossaint J, Moser M, et al. Distinct roles for talin-1 and kindlin-3 in LFA-1 extension and affinity regulation. Blood. 2012,119(18):4275-82. doi: 10.1182/blood-2011-08-373118
Read this paper
Kim WK, Sun Y, Do H, et al. Monocyte heterogeneity underlying phenotypic changes in monocytes according to SIV disease stage. J Leukoc Biol. 2010,87(4):557-67. doi: 10.1189/jlb.0209082
Read this paper
Roland CL, Dineen SP, Lynn KD, et al. Inhibition of vascular endothelial growth factor reduces angiogenesis and modulates immune cell infiltration of orthotopic breast cancer xenografts. Mol Cancer Ther. 2009,8(7):1761-71. doi: 10.1158/1535-7163.MCT-09-0280
Read this paper
Sorg H, Lorch B, Jaster R, et al. Early rise in inflammation and microcirculatory disorder determine the development of autoimmune pancreatitis in the MRL/Mp-mouse. Am J Physiol Gastrointest Liver Physiol. 2008,295(6):G1274-80. doi: 10.1152/ajpgi.90341.2008
Read this paper
Kim DD, Miwa T, Kimura Y, et al. Deficiency of decay-accelerating factor and complement receptor 1-related gene/protein y on murine platelets leads to complement-dependent clearance by the macrophage phagocytic receptor CRIg. Blood. 2008,112(4):1109-19. doi: 10.1182/blood-2008-01-134304
Read this paper
Ou R, Zhang M, Huang L, et al. Regulation of immune response and inflammatory reactions against viral infection by VCAM-1. J Virol. 2008,82(6):2952-65. doi: 10.1128/JVI.02191-07
Read this paper
Nakayama H, Yoshizaki F, Prinetti A, et al. Lyn-coupled LacCer-enriched lipid rafts are required for CD11b/CD18-mediated neutrophil phagocytosis of nonopsonized microorganisms. J Leukoc Biol. 2008,83(3):728-41.
Read this paper
Nutt SL, Metcalf D, D'Amico A, et al. Dynamic regulation of PU.1 expression in multipotent hematopoietic progenitors. J Exp Med. 2005,201(2):221-31.
Read this paper
Rogers C, Edelman ER, Simon DI. A mAb to the beta2-leukocyte integrin Mac-1 (CD11b/CD18) reduces intimal thickening after angioplasty or stent implantation in rabbits. Proc Natl Acad Sci U S A. 1998,95(17):10134-9.
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CD11b antibody [M1/70]

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