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CD11b antibody [M1/70.15] (PE)

GTX76470
GeneTex
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityMouse
TargetItgam
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Overview

  • Supplier
    GeneTex
  • Product Name
    CD11b antibody [M1/70.15] (PE)
  • Delivery Days Customer
    9
  • Antibody Specificity
    Mouse CD11b
  • Application Supplier Note
    For FACS: Use 0.1 ug to label 10^6 cells. Protocols are available upon request. Optimal dilutions/concentrations should be determined by the end user.
  • Applications
    Flow Cytometry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    M1/70.15
  • Concentration
    0.1 mg/ml
  • Conjugate
    RPE
  • Gene ID16409
  • Target name
    Itgam
  • Target description
    integrin alpha M
  • Target synonyms
    CD11 antigen-like family member B; Cd11b; CD11B (p170); CD11b/CD18; cell surface glycoprotein MAC-1 alpha subunit; cell surface glycoprotein MAC-1 subunit alpha; complement receptor type 3; CR; CR3; CR-3 alpha chain; CR3A; F730045J24Rik; integrin alpha-M; leukocyte adhesion receptor MO1; Ly-4; Ly-40; Mac-; MAC1; Mac-1; Mac-1 alpha; Mac-1a; macrophage antigen alpha
  • Host
    Rat
  • Isotype
    IgG2b
  • Scientific Description
    Recognises the murine CD11b cell surface antigen (also known as the alpha M integrin chain), a differentiation antigen expressed by granulocytes, monocytes, NK cells and tissue macrophages. The expression of CD11b increases during monocyte maturation and expression levels vary on tissue macrophages. Peritoneal macrophages are reported to express higher levels of CD11b than splenic macrophages. Clone M1/70.15 has been reported to block iC3b binding to its receptor (3).
  • Reactivity
    Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Extracellular DJ-1 induces sterile inflammation in the ischemic brain. Nakamura K et al., 2021 May, PLoS Biol
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  • Characteristics of fucose-containing polysaccharides from submerged fermentation of Agaricus blazei Murill.
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  • Trajectory of inflammatory and microglial activation markers in the postnatal rabbit brain following intrauterine endotoxin exposure. Zhang Z et al., 2018 Mar, Neurobiol Dis
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  • A Type II Arabinogalactan from Anoectochilus formosanus for G-CSF Production in Macrophages and Leukopenia Improvement in CT26-Bearing Mice Treated with 5-Fluorouracil. Yang LC et al., 2013, Evid Based Complement Alternat Med
    Read more