CD11b antibody [M1/70.15] (PE)
GTX76470
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityMouse
TargetItgam
Overview
- SupplierGeneTex
- Product NameCD11b antibody [M1/70.15] (PE)
- Delivery Days Customer9
- Application Supplier NoteFor FACS: Use 0.1 ug to label 10^6 cells. Protocols are available upon request. Optimal dilutions/concentrations should be determined by the end user.
- ApplicationsFlow Cytometry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDM1/70.15
- Concentration0.1 mg/ml
- ConjugateRPE
- Gene ID16409
- Target nameItgam
- Target descriptionintegrin alpha M
- Target synonymsCD11b/CD18, CR3, CR3A, Cd11b, F730045J24Rik, Ly-40, MAC1, Mac-1, Mac-1a, integrin alpha-M, CD11 antigen-like family member B, CD11B (p170), CR-3 alpha chain, Mac-1 alpha, cell surface glycoprotein MAC-1 alpha subunit, cell surface glycoprotein MAC-1 subunit alpha, complement receptor type 3, leukocyte adhesion receptor MO1, macrophage antigen alpha
- HostRat
- IsotypeIgG2b
- Scientific DescriptionRecognises the murine CD11b cell surface antigen (also known as the alpha M integrin chain), a differentiation antigen expressed by granulocytes, monocytes, NK cells and tissue macrophages. The expression of CD11b increases during monocyte maturation and expression levels vary on tissue macrophages. Peritoneal macrophages are reported to express higher levels of CD11b than splenic macrophages. Clone M1/70.15 has been reported to block iC3b binding to its receptor (3).
- ReactivityMouse
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- Nakamura K, Sakai S, Tsuyama J, et al. Extracellular DJ-1 induces sterile inflammation in the ischemic brain. PLoS Biol. 2021,19(5):e3000939. doi: 10.1371/journal.pbio.3000939Read this paper
- Wang HT, Yang LC, Yu HC, et al. Characteristics of fucose-containing polysaccharides from submerged fermentation of Agaricus blazei Murill. J Food Drug Anal. 2018,26(2):678-687. doi: 10.1016/j.jfda.2017.07.006Read this paper
- Zhang Z, Jyoti A, Balakrishnan B, et al. Trajectory of inflammatory and microglial activation markers in the postnatal rabbit brain following intrauterine endotoxin exposure. Neurobiol Dis. 2018,111:153-162. doi: 10.1016/j.nbd.2017.12.013Read this paper
- Yang LC, Lu TJ, Lin WC. A Type II Arabinogalactan from Anoectochilus formosanus for G-CSF Production in Macrophages and Leukopenia Improvement in CT26-Bearing Mice Treated with 5-Fluorouracil. Evid Based Complement Alternat Med. 2013,2013:458075. doi: 10.1155/2013/458075Read this paper
![FACS analysis of C57Bl/6 bone marrow cells using GTX80051 CD11b antibody [M1/70] (FITC). Solid line : Primary antibody Dashed line : FITC rat IgG2b isotype control Antibody amount : 0.5 microg](https://www.genetex.com/upload/website/prouct_img/normal/GTX80051/GTX80051_20201020_FACS_27_w_23061322_647.webp)
![FACS analysis of C57Bl/6 bone marrow cells using GTX80052 CD11b antibody [M1/70] (PE). Solid line : Primary antibody Dashed line : PE rat IgG2b isotype control Antibody amount : 0.125 microg](https://www.genetex.com/upload/website/prouct_img/normal/GTX80052/GTX80052_20201020_FACS_51_w_23061322_353.webp)
![FACS analysis of C57Bl/6 bone marrow cells using GTX57222 CD11b antibody [M1/70] (APC). Solid line : Primary antibody Dashed line : APC rat IgG2b isotype control Antibody amount : 0.125 microg](https://www.genetex.com/upload/website/prouct_img/normal/GTX57222/GTX57222_20201020_FACS_6_w_23061123_114.webp)