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CD11b antibody [OX-42]

GTX76060
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Rat
TargetItgam
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Overview

  • Supplier
    GeneTex
  • Product Name
    CD11b antibody [OX-42]
  • Delivery Days Customer
    9
  • Application Supplier Note
    IHC-Fr: 1/50-1/100. FACS: 1/50-1/100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    OX-42
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID25021
  • Target name
    Itgam
  • Target description
    integrin subunit alpha M
  • Target synonyms
    Cd11b, integrin alpha-M, integrin, alpha M
  • Host
    Mouse
  • Isotype
    IgG2a
  • Reactivity
    Human, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

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  • Truzzi F, Tibaldi C, Whittaker A, et al. Pro-Inflammatory Effect of Gliadins and Glutenins Extracted from Different Wheat Cultivars on an In Vitro 3D Intestinal Epithelium Model. Int J Mol Sci. 2020,22(1). doi: 10.3390/ijms22010172
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  • Aminzadeh A, Tekiyeh Maroof N, Mehrabani M, et al. Investigating The Alterations of Oxidative Stress Status, Antioxidant Defense Mechanisms, MAP Kinase and Mitochondrial Apoptotic Pathway in Adipose-Derived Mesenchymal Stem Cells from STZ Diabetic Rats. Cell J. 2020,22(Suppl 1):38-48. doi: 10.22074/cellj.2020.6958
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  • Bai N, Zhang Q, Zhang W, et al. G-protein-coupled estrogen receptor activation upregulates interleukin-1 receptor antagonist in the hippocampus after global cerebral ischemia: implications for neuronal self-defense. J Neuroinflammation. 2020,17(1):45. doi: 10.1186/s12974-020-1715-x
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  • Lin CH, Liao LY, Yang TY, et al. Microglia-Derived Adiposomes are Potential Targets for the Treatment of Ischemic Stroke. Cell Mol Neurobiol. 2019,39(5):591-604. doi: 10.1007/s10571-019-00665-9
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  • Bonfante R, Napimoga MH, Macedo CG, et al. The P2X7 Receptor, Cathepsin S and Fractalkine in the Trigeminal Subnucleus Caudalis Signal Persistent Hypernociception in Temporomandibular Rat Joints. Neuroscience. 2018,391:120-130. doi: 10.1016/j.neuroscience.2018.09.005
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  • Lin CH, Wang CH, Hsu SL, et al. Molecular Mechanisms Responsible for Neuron-Derived Conditioned Medium (NCM)-Mediated Protection of Ischemic Brain. PLoS One. 2016,11(1):e0146692. doi: 10.1371/journal.pone.0146692
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  • Nakajima H, Uchida K, Guerrero AR, et al. Transplantation of mesenchymal stem cells promotes an alternative pathway of macrophage activation and functional recovery after spinal cord injury. J Neurotrauma. 2012,29(8):1614-25. doi: 10.1089/neu.2011.2109
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  • Takahashi K, Watanabe M, Suekawa Y, et al. IL-1beta in the trigeminal subnucleus caudalis contributes to extra-territorial allodynia/hyperalgesia following a trigeminal nerve injury. Eur J Pain. 2011,15(5):467.e1-14. doi: 10.1016/j.ejpain.2010.10.006
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  • Zhao Z, Li Q, Hu J, et al. Lactosyl derivatives function in a rat model of severe burn shock by acting as antagonists against CD11b of integrin on leukocytes. Glycoconj J. 2009,26(2):173-88. doi: 10.1007/s10719-008-9174-0
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