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ProductsBack/CD18 antibody [MEM-148]
WB analysis of PMA-activated neutrophils (A) and monocytes (B) using GTX28220 CD18 antibody [MEM-148].The antibody MEM-148 recognizes the lower 65 to 70 kDa zone (activation marker) as well as the upper 78 to 96 kDa zone (CD18).
WB analysis of PMA-activated neutrophils (A) and monocytes (B) using GTX28220 CD18 antibody [MEM-148].The antibody MEM-148 recognizes the lower 65 to 70 kDa zone (activation marker) as well as the upper 78 to 96 kDa zone (CD18).
WB analysis of PMA-activated neutrophils (A) and monocytes (B) using GTX28220 CD18 antibody [MEM-148].The antibody MEM-148 recognizes the lower 65 to 70 kDa zone (activation marker) as well as the upper 78 to 96 kDa zone (CD18).

CD18 antibody [MEM-148]

GTX28220
GeneTex
ApplicationsFunctional Assay, Flow Cytometry, ImmunoPrecipitation, Western Blot
DownloadDatasheet
Product group Antibodies
ReactivityHuman
TargetITGB2
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Overview

  • Supplier
    GeneTex
  • Product Name
    CD18 antibody [MEM-148] - Orthogonal Validated
  • Delivery Days Customer
    9
  • Antibody Specificity
    This antibody recognizes an epitope on CD18 which is essentially inaccessible in intact integrin molecules on resting leukocytes, but is exposed on high-affinity state of LFA-1 or on unassociated CD18.,We do not recommend use of this product for Pig.
  • Applications
    Functional Assay, Flow Cytometry, ImmunoPrecipitation, Western Blot
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    MEM-148
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID3689
  • Target name
    ITGB2
  • Target description
    integrin subunit beta 2
  • Target synonyms
    CD18; cell surface adhesion glycoprotein (LFA-1/CR3/P150,959 beta subunit precursor); complement component 3 receptor 3 and 4 subunit; complement receptor C3 beta-subunit; integrin beta chain, beta 2; integrin beta-2; integrin, beta 2 (complement component 3 receptor 3 and 4 subunit); LAD; LCAMB; leukocyte cell adhesion molecule CD18; leukocyte-associated antigens CD18/11A, CD18/11B, CD18/11C; LFA-1; MAC-1; MF17; MFI7; truncated integrin beta-2
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP05107
  • Protein Name
    Integrin beta-2
  • Scientific Description
    This gene encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Distinct binding affinities of Mac-1 and LFA-1 in neutrophil activation. Li N et al., 2013 Apr 15, J Immunol
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