CD1b(100-1A5), 0.2mg/mL [26628-22-8]

Biotium

CD1b(100-1A5), 0.2mg/mL [26628-22-8]

9

Flow Cytometry

26628-22-8

Research Use Only

Monoclonal

100-1A5

0.2 mg/ml

CD1B

CD1b molecule

CD1, CD1A, R1, T-cell surface glycoprotein CD1b, CD1B antigen, b polypeptide, cortical thymocyte antigen CD1B, differentiation antigen CD1-alpha-3

Mouse

IgM

T-cell surface glycoprotein CD1b

The mouse monoclonal antibody recognizes CD1b, a 44 kDa type I glycoprotein associated with beta2-microglobulin (Workshop IV; Code T015). It is expressed on dendritic cells, Langerhans cells, thymocytes, and T acute lymphoblastic leukemia cells. The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 membrane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. Constitutive endocytosis of CD1B molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. CD1B is also expressed in interdigitating cells.This antibody is available purified with BSA/azide at 200 ug/mL, or BSA/azide-free at 1 mg/mL.

Animal

Bovine, Human, Mouse

2°C to 8°C,RT

41116161