CD27 antibody [MSVA-027M] HistoMAX(tm)

GeneTex

CD27 antibody [MSVA-027M] HistoMAX(tm)

9

IHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

MSVA-027M

0.2 mg/ml

Unconjugated

Liquid

CD27

CD27 molecule

CD27 antigen; CD27L receptor; S152; S152. LPFS2; T cell activation antigen S152; T14; T-cell activation antigen CD27; TNFRSF7; Tp55; tumor necrosis factor receptor superfamily, member 7

Mouse

IgG2b

CD27 antigen

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]

Human

-20°C or -80°C,2°C to 8°C

12352203