FACS analysis of human peripheral blood lymphocytes using GTX01457-15 CD27 antibody [O323] (APC-Cy7). Solid lone : primary antibody Dashed line : isotype control antibody amount : 0.125 microg (5 microl)
FACS analysis of human peripheral blood lymphocytes using GTX01457-15 CD27 antibody [O323] (APC-Cy7). Solid lone : primary antibody Dashed line : isotype control antibody amount : 0.125 microg (5 microl)
CD27 antibody [O323] (APC-Cy7)
GTX01457-15
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityHuman, Monkey, Primate
TargetCD27
Overview
- SupplierGeneTex
- Product NameCD27 antibody [O323] (APC-Cy7)
- Delivery Days Customer9
- Application Supplier NoteFACS: 0.125 microg (5 microl) for 105-108 cells in 100 microl sample per test. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDO323
- Concentration0.025 mg/ml
- ConjugateDouble Conjugated
- FormulationLiquid
- Gene ID939
- Target nameCD27
- Target descriptionCD27 molecule
- Target synonymsCD27 antigen; CD27L receptor; S152; S152. LPFS2; T cell activation antigen S152; T14; T-cell activation antigen CD27; TNFRSF7; Tp55; tumor necrosis factor receptor superfamily, member 7
- HostMouse
- IsotypeIgG1
- Protein IDP26842
- Protein NameCD27 antigen
- Scientific DescriptionThe protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]
- ReactivityHuman, Monkey, Primate
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
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- A SARS-CoV-2 neutralizing antibody protects from lung pathology in a COVID-19 hamster model. Kreye J et al., 2020 Aug 16, bioRxivRead more
- Ovarian granulosa cell tumor characterization identifies FOXL2 as an immunotherapeutic target. Pierini S et al., 2020 Aug 20, JCI InsightRead more
- Single-cell TCR sequencing reveals phenotypically diverse clonally expanded cells harboring inducible HIV proviruses during ART. Gantner P et al., 2020 Aug 14, Nat CommunRead more
- Early ART in Acute HIV-1 Infection: Impact on the B-Cell Compartment. Badura R et al., 2020, Front Cell Infect MicrobiolRead more
- A 34-Marker Panel for Imaging Mass Cytometric Analysis of Human Snap-Frozen Tissue. Guo N et al., 2020, Front ImmunolRead more
- Sialyl-Lewis(X) Glycoantigen Is Enriched on Cells with Persistent HIV Transcription during Therapy. Colomb F et al., 2020 Aug 4, Cell RepRead more
- Complex Autoinflammatory Syndrome Unveils Fundamental Principles of JAK1 Kinase Transcriptional and Biochemical Function. Gruber CN et al., 2020 Sep 15, ImmunityRead more
- Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes. Zhou T et al., 2020 Jul 21, SSRNRead more
- Atypical memory B-cells and autoantibodies correlate with anemia during Plasmodium vivax complicated infections. Rivera-Correa J et al., 2020 Jul, PLoS Negl Trop DisRead more