![FACS analysis of human peripheral blood lymphocytes using GTX01457-08 CD27 antibody [O323] (PE). Solid lone : primary antibody Dashed line : isotype control antibody amount : 0.25 microg (5 microl) FACS analysis of human peripheral blood lymphocytes using GTX01457-08 CD27 antibody [O323] (PE). Solid lone : primary antibody Dashed line : isotype control antibody amount : 0.25 microg (5 microl)](https://www.genetex.com/upload/website/prouct_img/normal/GTX01457-08/GTX01457-08_20200428_FACS104_w_23053121_387.webp)
FACS analysis of human peripheral blood lymphocytes using GTX01457-08 CD27 antibody [O323] (PE). Solid lone : primary antibody Dashed line : isotype control antibody amount : 0.25 microg (5 microl)
CD27 antibody [O323] (PE)
GTX01457-08
ApplicationsFlow Cytometry
Product group Antibodies
TargetCD27
Overview
- SupplierGeneTex
- Product NameCD27 antibody [O323] (PE)
- Delivery Days Customer9
- Application Supplier NoteFACS: 0.25 microg (5 microl) for 105-108 cells in 100 microl sample per test. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDO323
- Concentration0.05 mg/ml
- ConjugateRPE
- Gene ID939
- Target nameCD27
- Target descriptionCD27 molecule
- Target synonymsS152, S152. LPFS2, T14, TNFRSF7, Tp55, CD27 antigen, CD27L receptor, T cell activation antigen S152, T-cell activation antigen CD27, tumor necrosis factor receptor superfamily, member 7
- HostMouse
- IsotypeIgG1
- Protein IDP26842
- Protein NameCD27 antigen
- Scientific DescriptionThe protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
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- Kreye J, Reincke SM, Kornau HC, et al. A SARS-CoV-2 neutralizing antibody protects from lung pathology in a COVID-19 hamster model. bioRxiv. 2020,:pii: 2020.08.15.252320. doi: 10.1101/2020.08.15.252320.Read this paper
- Pierini S, Tanyi JL, Simpkins F, et al. Ovarian granulosa cell tumor characterization identifies FOXL2 as an immunotherapeutic target. JCI Insight. 2020,5(16):pii: 136773. doi: 10.1172/jci.insight.136773.Read this paper
- Gantner P, Pagliuzza A, Pardons M, et al. Single-cell TCR sequencing reveals phenotypically diverse clonally expanded cells harboring inducible HIV proviruses during ART. Nat Commun. 2020,11(1):4089. doi: 10.1038/s41467-020-17898-8Read this paper
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- Colomb F, Giron LB, Kuri-Cervantes L, et al. Sialyl-Lewis(X) Glycoantigen Is Enriched on Cells with Persistent HIV Transcription during Therapy. Cell Rep. 2020,32(5):107991. doi: 10.1016/j.celrep.2020.107991Read this paper
- Gruber CN, Calis JJA, Buta S, et al. Complex Autoinflammatory Syndrome Unveils Fundamental Principles of JAK1 Kinase Transcriptional and Biochemical Function. Immunity. 2020,53(3):672-684.e11. doi: 10.1016/j.immuni.2020.07.006Read this paper
- Zhou T, Teng IT, Olia AS, et al. Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes. SSRN. 2020,:3639618. doi: 10.2139/ssrn.3639618Read this paper
- Rivera-Correa J, Yasnot-Acosta MF, Tovar NC, et al. Atypical memory B-cells and autoantibodies correlate with anemia during Plasmodium vivax complicated infections. PLoS Negl Trop Dis. 2020,14(7):e0008466. doi: 10.1371/journal.pntd.0008466Read this paper




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