CD27 Antibody
ORB533982
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetCD27
Overview
- SupplierBiorbyt
- Product NameCD27 Antibody
- Delivery Days Customer16
- Application Supplier NoteThe stated application concentrations are suggested starting points. Titration of the recombinant CD27 antibody may be required due to differences in protocols and secondary/substrate sensitivity.1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- Applications SupplierImmunohistochemistry (FFPE): 0.5-1ug/ml for 30 min at RT,Prediluted IHC only format : incubate for 30 min at RT (1) IHC-P
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDCDLA27-1R
- ConjugateUnconjugated
- Gene ID939
- Target nameCD27
- Target descriptionCD27 molecule
- Target synonymsCD27 antigen; CD27L receptor; S152; S152. LPFS2; T cell activation antigen S152; T14; T-cell activation antigen CD27; TNFRSF7; Tp55; tumor necrosis factor receptor superfamily, member 7
- HostRabbit
- IsotypeIgG
- Protein IDP26842
- Protein NameCD27 antigen
- Scientific DescriptionThe protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. CD27 transduces signals that lead to the activation of NF-kB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [Wiki]
- ReactivityHuman
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352203