Bio-Connect

CD27 Antibody

Research Use Only
ORB533982
Biorbyt
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetCD27
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Overview

  • Supplier
    Biorbyt
  • Product Name
    CD27 Antibody
  • Delivery Days Customer
    16
  • Application Supplier Note
    The stated application concentrations are suggested starting points. Titration of the recombinant CD27 antibody may be required due to differences in protocols and secondary/substrate sensitivity.1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
  • Applications
    ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Applications Supplier
    Immunohistochemistry (FFPE): 0.5-1ug/ml for 30 min at RT,Prediluted IHC only format : incubate for 30 min at RT (1) IHC-P
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    CDLA27-1R
  • Conjugate
    Unconjugated
  • Gene ID939
  • Target name
    CD27
  • Target description
    CD27 molecule
  • Target synonyms
    CD27 antigen; CD27L receptor; S152; S152. LPFS2; T cell activation antigen S152; T14; T-cell activation antigen CD27; TNFRSF7; Tp55; tumor necrosis factor receptor superfamily, member 7
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP26842
  • Protein Name
    CD27 antigen
  • Scientific Description
    The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. CD27 transduces signals that lead to the activation of NF-kB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [Wiki]
  • Reactivity
    Human
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352203