CD63 antibody [CLBGran/12] (FITC)
GTX44174
Overview
- SupplierGeneTex
- Product NameCD63 antibody [CLBGran/12] (FITC)
- Delivery Days Customer9
- Antibody SpecificityThe molecular weight of the recognized platelet form of CD63 is 40 to 55 kDa. CLBGran/12 reacts withmost peripheral blood cells including activated platelets, lymphoid, myeloid and endothelial cells, except forred blood cells and resting T cells. The CD63
- Application Supplier NoteFACS: 20 microL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDCLBGran/12
- ConjugateFITC
- FormulationLiquid
- Gene ID967
- Target nameCD63
- Target descriptionCD63 molecule
- Target synonymsCD63 antigen; CD63 antigen (melanoma 1 antigen); granulophysin; LAMP-3; lysosomal-associated membrane protein 3; lysosome-associated membrane glycoprotein 3; ME491; melanoma-associated antigen ME491; melanoma-associated antigen MLA1; MLA1; ocular melanoma-associated antigen; OMA81H; tetraspanin-30; TSPAN30; tspan-30
- HostMouse
- IsotypeIgG1
- Protein IDP08962
- Protein NameCD63 antigen
- Scientific DescriptionThe protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Apr 2012]
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- Crosstalk between tumor cells and lymphocytes modulates heparanase expression. Theodoro TR et al., 2019 Mar 29, J Transl MedRead more