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CD63 antibody [CLBGran/12] (FITC)

Research Use Only
GTX44174
GeneTex
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityHuman
TargetCD63
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Overview

  • Supplier
    GeneTex
  • Product Name
    CD63 antibody [CLBGran/12] (FITC)
  • Delivery Days Customer
    9
  • Antibody Specificity
    The molecular weight of the recognized platelet form of CD63 is 40 to 55 kDa. CLBGran/12 reacts withmost peripheral blood cells including activated platelets, lymphoid, myeloid and endothelial cells, except forred blood cells and resting T cells. The CD63
  • Application Supplier Note
    FACS: 20 microL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    CLBGran/12
  • Conjugate
    FITC
  • Formulation
    Liquid
  • Gene ID967
  • Target name
    CD63
  • Target description
    CD63 molecule
  • Target synonyms
    CD63 antigen; CD63 antigen (melanoma 1 antigen); granulophysin; LAMP-3; lysosomal-associated membrane protein 3; lysosome-associated membrane glycoprotein 3; ME491; melanoma-associated antigen ME491; melanoma-associated antigen MLA1; MLA1; ocular melanoma-associated antigen; OMA81H; tetraspanin-30; TSPAN30; tspan-30
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP08962
  • Protein Name
    CD63 antigen
  • Scientific Description
    The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Apr 2012]
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Crosstalk between tumor cells and lymphocytes modulates heparanase expression. Theodoro TR et al., 2019 Mar 29, J Transl Med
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