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Immunohistochemistry (IHC) analyzes of CD63 pAb in paraffin-embedded human lung carcinoma tissue.
Immunohistochemistry (IHC) analyzes of CD63 pAb in paraffin-embedded human lung carcinoma tissue.
Immunohistochemistry (IHC) analyzes of CD63 pAb in paraffin-embedded human lung carcinoma tissue.

CD63 antibody

Research Use Only
GTX17441
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetCD63
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Overview

  • Supplier
    GeneTex
  • Product Name
    CD63 antibody
  • Delivery Days Customer
    9
  • Antibody Specificity
    CD63 (K156) pAb detects endogenous levels of CD63 protein.
  • Application Supplier Note
    WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID967
  • Target name
    CD63
  • Target description
    CD63 molecule
  • Target synonyms
    CD63 antigen; CD63 antigen (melanoma 1 antigen); granulophysin; LAMP-3; lysosomal-associated membrane protein 3; lysosome-associated membrane glycoprotein 3; ME491; melanoma-associated antigen ME491; melanoma-associated antigen MLA1; MLA1; ocular melanoma-associated antigen; OMA81H; tetraspanin-30; TSPAN30; tspan-30
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP08962
  • Protein Name
    CD63 antigen
  • Scientific Description
    The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Apr 2012]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Circ_0006790 carried by bone marrow mesenchymal stem cell-derived exosomes regulates S100A11 DNA methylation through binding to CBX7 in pancreatic ductal adenocarcinoma. Gao G et al., 2022, Am J Cancer Res
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  • Exosomes derived from olfactory ensheathing cells provided neuroprotection for spinal cord injury by switching the phenotype of macrophages/microglia. Fan H et al., 2022 May, Bioeng Transl Med
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  • Comparison of separation methods for tissue-derived extracellular vesicles in the liver, heart, and skeletal muscle. Matejovic A et al., 2021 Feb, FEBS Open Bio
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  • miR-1975 serves as an indicator of clinical severity upon influenza infection. Liu YM et al., 2021 Jan, Eur J Clin Microbiol Infect Dis
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  • Exosome-delivered and Y RNA-derived small RNA suppresses influenza virus replication. Liu YM et al., 2019 Aug 15, J Biomed Sci
    Read more
  • EIF3C-enhanced exosome secretion promotes angiogenesis and tumorigenesis of human hepatocellular carcinoma. Lee HY et al., 2018 Mar 2, Oncotarget
    Read more
  • Exosomal TGF-beta1 is correlated with lymphatic metastasis of gastric cancers. Yen EY et al., 2017, Am J Cancer Res
    Read more
  • Circulating extracellular vesicles with specific proteome and liver microRNAs are potential biomarkers for liver injury in experimental fatty liver disease. Povero D et al., 2014, PLoS One
    Read more