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CD63 antibody [MEM-259] (PerCP-Cy5.5)

GTX28219-11
GeneTex
ApplicationsFlow Cytometry
Product group Antibodies
TargetCD63
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Overview

  • Supplier
    GeneTex
  • Product Name
    CD63 antibody [MEM-259] (PerCP-Cy5.5)
  • Delivery Days Customer
    9
  • Application Supplier Note
    FACS: 4 microl reagent / 100 microl of whole blood or 106 cells in a suspension. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    MEM-259
  • Conjugate
    Double Conjugated
  • Gene ID967
  • Target name
    CD63
  • Target description
    CD63 molecule
  • Target synonyms
    CD63 antigen; CD63 antigen (melanoma 1 antigen); granulophysin; LAMP-3; lysosomal-associated membrane protein 3; lysosome-associated membrane glycoprotein 3; ME491; melanoma-associated antigen ME491; melanoma-associated antigen MLA1; MLA1; ocular melanoma-associated antigen; OMA81H; tetraspanin-30; TSPAN30; tspan-30
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP08962
  • Protein Name
    CD63 antigen
  • Scientific Description
    The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Apr 2012]
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • An intercellular transfer of telomeres rescues T cells from senescence and promotes long-term immunological memory.
    Read more
  • Plasma extracellular vesicle derived protein profile predicting and monitoring immunotherapeutic outcomes of gastric cancer. Zhang C et al., 2022 Apr, J Extracell Vesicles
    Read more
  • Cell-Matrix Interactions Regulate Functional Extracellular Vesicle Secretion from Mesenchymal Stromal Cells.
    Read more
  • LINC00511 drives invasive behavior in hepatocellular carcinoma by regulating exosome secretion and invadopodia formation. Peng X et al., 2021 Jun 4, J Exp Clin Cancer Res
    Read more
  • IKKbeta activation promotes amphisome formation and extracellular vesicle secretion in tumor cells. Peng X et al., 2021 Jan, Biochim Biophys Acta Mol Cell Res
    Read more
  • Long non-coding RNA HOTAIR promotes exosome secretion by regulating RAB35 and SNAP23 in hepatocellular carcinoma. Yang L et al., 2019 Apr 3, Mol Cancer
    Read more
  • Annexin A1 regulates EGFR activity and alters EGFR-containing tumour-derived exosomes in head and neck cancers. Raulf N et al., 2018 Oct, Eur J Cancer
    Read more
  • beta2-microglobulin amyloid fibrils are nanoparticles that disrupt lysosomal membrane protein trafficking and inhibit protein degradation by lysosomes. Jakhria T et al., 2014 Dec 26, J Biol Chem
    Read more

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