Bio-Connect

CENPF antibody [14C10 1D8]

GTX70137
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetCENPF
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    CENPF antibody [14C10 1D8] - Orthogonal Validated
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    14C10 1D8
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID1063
  • Target name
    CENPF
  • Target description
    centromere protein F
  • Target synonyms
    CENF, CILD31, PRO1779, STROMS, hcp-1, centromere protein F, AH antigen, CENP-F kinetochore protein, cell-cycle-dependent 350K nuclear protein, centromere protein F, 350/400kDa, kinetochore protein CENPF, mitosin
  • Host
    Mouse
  • Isotype
    IgG2a
  • Protein IDP49454
  • Protein Name
    Centromere protein F
  • Scientific Description
    This gene encodes a protein that associates with the centromere-kinetochore complex. The protein is a component of the nuclear matrix during the G2 phase of interphase. In late G2 the protein associates with the kinetochore and maintains this association through early anaphase. It localizes to the spindle midzone and the intracellular bridge in late anaphase and telophase, respectively, and is thought to be subsequently degraded. The localization of this protein suggests that it may play a role in chromosome segregation during mitotis. It is thought to form either a homodimer or heterodimer. Autoantibodies against this protein have been found in patients with cancer or graft versus host disease. [provided by RefSeq, Jul 2008]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Does protein expression predict recurrence of benign World Health Organization grade I meningioma? Kaerjae V et al., 2010 Feb, Hum Pathol
    Read more
  • M phase phosphoprotein 1 is a human plus-end-directed kinesin-related protein required for cytokinesis. Abaza A et al., 2003 Jul 25, J Biol Chem
    Read more
  • Mitosin, a novel marker of cell proliferation and early recurrence in intracranial meningiomas. Konstantinidou AE et al., 2003 Jan, Histol Histopathol
    Read more
  • Localization of human SMC1 protein at kinetochores. Gregson HC et al., 2002, Chromosome Res
    Read more
  • Molecular markers of endometrial epithelial cell mitogenesis mediated by the Sp/Krueppel-like factor BTEB1. Simmen RC et al., 2002 Feb, DNA Cell Biol
    Read more
  • Nonperiodic activity of the human anaphase-promoting complex-Cdh1 ubiquitin ligase results in continuous DNA synthesis uncoupled from mitosis. Sorensen CS et al., 2000 Oct, Mol Cell Biol
    Read more