CENPF antibody [14C10 1D8]
GTX70137
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetCENPF
Overview
- SupplierGeneTex
- Product NameCENPF antibody [14C10 1D8] - Orthogonal Validated
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID14C10 1D8
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID1063
- Target nameCENPF
- Target descriptioncentromere protein F
- Target synonymsCENF, CILD31, PRO1779, STROMS, hcp-1, centromere protein F, AH antigen, CENP-F kinetochore protein, cell-cycle-dependent 350K nuclear protein, centromere protein F, 350/400kDa, kinetochore protein CENPF, mitosin
- HostMouse
- IsotypeIgG2a
- Protein IDP49454
- Protein NameCentromere protein F
- Scientific DescriptionThis gene encodes a protein that associates with the centromere-kinetochore complex. The protein is a component of the nuclear matrix during the G2 phase of interphase. In late G2 the protein associates with the kinetochore and maintains this association through early anaphase. It localizes to the spindle midzone and the intracellular bridge in late anaphase and telophase, respectively, and is thought to be subsequently degraded. The localization of this protein suggests that it may play a role in chromosome segregation during mitotis. It is thought to form either a homodimer or heterodimer. Autoantibodies against this protein have been found in patients with cancer or graft versus host disease. [provided by RefSeq, Jul 2008]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Does protein expression predict recurrence of benign World Health Organization grade I meningioma? Kaerjae V et al., 2010 Feb, Hum PatholRead more
- M phase phosphoprotein 1 is a human plus-end-directed kinesin-related protein required for cytokinesis. Abaza A et al., 2003 Jul 25, J Biol ChemRead more
- Mitosin, a novel marker of cell proliferation and early recurrence in intracranial meningiomas. Konstantinidou AE et al., 2003 Jan, Histol HistopatholRead more
- Localization of human SMC1 protein at kinetochores. Gregson HC et al., 2002, Chromosome ResRead more
- Molecular markers of endometrial epithelial cell mitogenesis mediated by the Sp/Krueppel-like factor BTEB1. Simmen RC et al., 2002 Feb, DNA Cell BiolRead more
- Nonperiodic activity of the human anaphase-promoting complex-Cdh1 ubiquitin ligase results in continuous DNA synthesis uncoupled from mitosis. Sorensen CS et al., 2000 Oct, Mol Cell BiolRead more






