Western blot analysis of extracts of various cell lines using CKAP5 Polyclonal Antibody at dilution of 1:1000.
Western blot analysis of extracts of various cell lines using CKAP5 Polyclonal Antibody at dilution of 1:1000.
CKAP5 Polyclonal Antibody
E-AB-63010
Product group Antibodies
Overview
- SupplierElabscience
- Product NameCKAP5 Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionThis gene encodes a cytoskeleton-associated protein which belongs to the TOG/XMAP215 family. The N-terminal half of this protein contains a microtubule-binding domain and the C-terminal half contains a KXGS motif for binding tubulin dimers. This protein has two distinct roles in spindle formation; it protects kinetochore microtubules from depolymerization and plays an essential role in centrosomal microtubule assembly. This protein may be necessary for the proper interaction of microtubules with the cell cortex for directional cell movement. It also plays a role in translation of the myelin basic protein (MBP) mRNA by interacting with heterogeneous nuclear ribonucleoprotein (hnRNP) A2, which associates with MBP. Alternatively spliced transcript variants encoding different isoforms have been identified.
- UNSPSC12352203