Claudin 1 antibody
GTX134842
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetCLDN1
Overview
- SupplierGeneTex
- Product NameClaudin 1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.06 mg/ml
- ConjugateUnconjugated
- Gene ID9076
- Target nameCLDN1
- Target descriptionclaudin 1
- Target synonymsclaudin-1; CLD1; ILVASC; SEMP1; senescence-associated epithelial membrane protein 1
- HostRabbit
- IsotypeIgG
- Protein IDO95832
- Protein NameClaudin-1
- Scientific DescriptionTight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome. [provided by RefSeq, Jul 2008]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Effect of heated tobacco products and traditional cigarettes on pulmonary toxicity and SARS-CoV-2-induced lung injury.Read more
- Immortalized human choroid plexus endothelial cells enable an advanced endothelial-epithelial two-cell type in vitro model of the choroid plexus. Muranyi W et al., 2022 Jun 17, iScienceRead more
- Cleavage stimulation factor 2 promotes malignant progression of liver hepatocellular carcinoma by activating phosphatidylinositol 3-kinase/protein kinase B/mammalian target of rapamycin pathway. Zhang MH et al., 2022 Apr, BioengineeredRead more
- CD4+/IL-4+ lymphocytes of the lamina propria and substance P promote colonic protection during acute stress. Arciniega-Martinez IM et al., 2022 Feb, Mol Med RepRead more
- A Fucoxanthinol Induces Apoptosis in a Pancreatic Intraepithelial Neoplasia Cell. Terasaki M et al., 2021 Mar-Apr, Cancer Genomics ProteomicsRead more