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IHC-P analysis of human liver tissue using GTX54539 Claudin 1 antibody. Right : Primary antibody Left : Negative control without primary antibody Antigen retrieval : 10mM sodium citrate (pH 6.0), microwaved for 8-15 min Dilution : 1:20
IHC-P analysis of human liver tissue using GTX54539 Claudin 1 antibody. Right : Primary antibody Left : Negative control without primary antibody Antigen retrieval : 10mM sodium citrate (pH 6.0), microwaved for 8-15 min Dilution : 1:20
IHC-P analysis of human liver tissue using GTX54539 Claudin 1 antibody. Right : Primary antibody Left : Negative control without primary antibody Antigen retrieval : 10mM sodium citrate (pH 6.0), microwaved for 8-15 min Dilution : 1:20

Claudin 1 antibody

GTX54539
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityAvian, Bovine, Canine, Human, Mouse, Rabbit, Rat
TargetCLDN1
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Overview

  • Supplier
    GeneTex
  • Product Name
    Claudin 1 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1-2 microg/mL. ICC/IF: 15-20 microg/mL. IHC-P: 1:10-1:100. ELISA: 0.1-1 microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.25 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID9076
  • Target name
    CLDN1
  • Target description
    claudin 1
  • Target synonyms
    claudin-1; CLD1; ILVASC; SEMP1; senescence-associated epithelial membrane protein 1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO95832
  • Protein Name
    Claudin-1
  • Scientific Description
    Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome. [provided by RefSeq, Jul 2008]
  • Reactivity
    Avian, Bovine, Canine, Human, Mouse, Rabbit, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Fucose ameliorates the proinflammatory property of Fusobacterium nucleatum in colitis via altering its metabolism.
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  • Diallyl Disulfide (DADS) Ameliorates Intestinal Candida albicans Infection by Modulating the Gut microbiota and Metabolites and Providing Intestinal Protection in Mice. Hu W et al., 2021, Front Cell Infect Microbiol
    Read more
  • Alterations in the gut microbiota and metabolic profiles coincide with intestinal damage in mice with a bloodborne Candida albicans infection. Hu W et al., 2021 May, Microb Pathog
    Read more
  • Cytoplasmic aryl hydrocarbon receptor regulates glycogen synthase kinase 3 beta, accelerates vimentin degradation, and suppresses epithelial-mesenchymal transition in non-small cell lung cancer cells. Li CH et al., 2017 May, Arch Toxicol
    Read more