
WB analysis of various lysates using GTX54539 Claudin 1 antibody. Lane 1 : Rat liver tissue lysate Lane 2 : Rat kidney tissue lysate Lane 3 : MDCK whole cell lysate Lane 4 : Caco-2 whole cell lysate Lane 5 : Mouse hepatocytes
Claudin 1 antibody
GTX54539
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityAvian, Bovine, Canine, Human, Mouse, Rabbit, Rat
TargetCLDN1
Overview
- SupplierGeneTex
- Product NameClaudin 1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1-2 microg/mL. ICC/IF: 15-20 microg/mL. IHC-P: 1:10-1:100. ELISA: 0.1-1 microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.25 mg/ml
- ConjugateUnconjugated
- Gene ID9076
- Target nameCLDN1
- Target descriptionclaudin 1
- Target synonymsCLD1, ILVASC, SEMP1, claudin-1, senescence-associated epithelial membrane protein 1
- HostRabbit
- IsotypeIgG
- Protein IDO95832
- Protein NameClaudin-1
- Scientific DescriptionTight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome. [provided by RefSeq, Jul 2008]
- ReactivityAvian, Bovine, Canine, Human, Mouse, Rabbit, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
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- Hu W, Huang L, Zhou Z, et al. Diallyl Disulfide (DADS) Ameliorates Intestinal Candida albicans Infection by Modulating the Gut microbiota and Metabolites and Providing Intestinal Protection in Mice. Front Cell Infect Microbiol. 2021,11:743454. doi: 10.3389/fcimb.2021.743454Read this paper
- Hu W, Xu D, Zhou Z, et al. Alterations in the gut microbiota and metabolic profiles coincide with intestinal damage in mice with a bloodborne Candida albicans infection. Microb Pathog. 2021,154:104826. doi: 10.1016/j.micpath.2021.104826Read this paper
- Li CH, Liu CW, Tsai CH, et al. Cytoplasmic aryl hydrocarbon receptor regulates glycogen synthase kinase 3 beta, accelerates vimentin degradation, and suppresses epithelial-mesenchymal transition in non-small cell lung cancer cells. Arch Toxicol. 2017,91(5):2165-2178. doi: 10.1007/s00204-016-1870-0Read this paper








