Western blot analysis of extracts from HeLa cells, using Collagen IV antibody.
Western blot analysis of extracts from HeLa cells, using Collagen IV antibody.
COL4A1 Antibody
CSB-PA975386
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetCOL4A1
Overview
- SupplierCusabio
- Product NameCOL4A1 Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID1282
- Target nameCOL4A1
- Target descriptioncollagen type IV alpha 1 chain
- Target synonymsarresten; BSVD; BSVD1; COL4A1 NC1 domain; COL4A1s; collagen alpha-1(IV) chain; collagen IV, alpha-1 polypeptide; collagen of basement membrane, alpha-1 chain; PADMAL; RATOR
- HostRabbit
- IsotypeIgG
- Protein IDP02462
- Protein NameCollagen alpha-1(IV) chain
- Scientific DescriptionType IV collagen is the major structural component of glomerular basement membranes (GBM), forming a chicken-wire meshwork together with laminins, proteoglycans and entactin/nidogen. Arresten, comprising the C-terminal NC1 domain, inhibits angiogenesis and tumor formation. The C-terminal half is found to possess the anti-angiogenic activity. Specifically inhibits endothelial cell proliferation, migration and tube formation. Inhibits expression of hypoxia-inducible factor 1alpha and ERK1/2 and p38 MAPK activation. Ligand for alpha1/beta1 integrin. Mary K. Chelberg, Cancer Res., Sep 1989; 49: 4796 - 4802. Patricia L. Graham, J. Cell Biol., Jun 1997; 137: 1171. PJ Lein, J. Cell Biol., Apr 1991; 113: 417. EC Tsilibary, J. Biol. Chem., Dec 1988; 263: 19112 - 19118.
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C
- UNSPSC12352203