Bio-Connect
IHC-P analysis of human lung tissue section using GTX20292 Collagen I antibody. Antigen retrieval : user optimized Dilution : 1:400 Localization : Strong staining was observed in the extracellular matrix of the lung. Epithelial cells were negative. Staining : antibody as precipitated red signal with a hematoxylin purple nuclear counterstain.
IHC-P analysis of human lung tissue section using GTX20292 Collagen I antibody. Antigen retrieval : user optimized Dilution : 1:400 Localization : Strong staining was observed in the extracellular matrix of the lung. Epithelial cells were negative. Staining : antibody as precipitated red signal with a hematoxylin purple nuclear counterstain.
IHC-P analysis of human lung tissue section using GTX20292 Collagen I antibody. Antigen retrieval : user optimized Dilution : 1:400 Localization : Strong staining was observed in the extracellular matrix of the lung. Epithelial cells were negative. Staining : antibody as precipitated red signal with a hematoxylin purple nuclear counterstain.

Collagen I antibody

GTX20292
GeneTex
ApplicationsDot Blot, Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin, Other Application
Product group Antibodies
TargetCOL1A1
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    Collagen I antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:1000-1:10000. IHC-P: 1:50-1:200. IP: 1:100. ELISA: 1:5000-1:50000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Dot Blot, Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin, Other Application
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID1277
  • Target name
    COL1A1
  • Target description
    collagen type I alpha 1 chain
  • Target synonyms
    CAFYD, EDSARTH1, EDSC, OI1, OI2, OI3, OI4, collagen alpha-1(I) chain, alpha-1 type I collagen, alpha1(I) procollagen, collagen Col1-ColIII-1, collagen Col1-ColIII-2, collagen alpha 1 chain type I, collagen alpha-1(I) chain preproprotein, collagen of skin, tendon and bone, alpha-1 chain, collagen, type I, alpha 1, pro-alpha-1 collagen type 1, type I proalpha 1, type I procollagen alpha 1 chain
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP02452
  • Protein Name
    Collagen alpha-1(I) chain
  • Scientific Description
    Collagens are highly conserved throughout evolution and are characterized by an uninterrupted Glycine-X-Y triplet repeat that is a necessary part of the triple helical structure. For these reasons it is often extremely difficult to generate antibodies with specificities to collagens. The development of type specific antibodies is dependent on NON-DENATURED three-dimensional epitopes. This preparation results in a native conformation of the protein.
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Li YJ, Shi JR, Li SC, et al. Phosphodiesterase type 10A inhibitor attenuates lung fibrosis by targeting myofibroblast activation. iScience. 2023,26(5):106586. doi: 10.1016/j.isci.2023.106586
    Read this paper
  • Chen CS, Hsu YA, Lin CH, et al. Fallopia Japonica and Prunella vulgaris inhibit myopia progression by suppressing AKT and NFκB mediated inflammatory reactions. BMC Complement Med Ther. 2022,22(1):271. doi: 10.1186/s12906-022-03747-2
    Read this paper
  • Ku H, Chen JJ, Hu M, et al. Myopia Development in Tree Shrew Is Associated with Chronic Inflammatory Reactions. Curr Issues Mol Biol. 2022,44(9):4303-4313. doi: 10.3390/cimb44090296
    Read this paper
  • Heo JY, Do JY, Lho Y, et al. TGF-β1 Receptor Inhibitor SB525334 Attenuates the Epithelial to Mesenchymal Transition of Peritoneal Mesothelial Cells via the TGF-β1 Signaling Pathway. Biomedicines. 2021,9(7). doi: 10.3390/biomedicines9070839
    Read this paper
  • Tien PT, Lin CH, Chen CS, et al. Diacerein Inhibits Myopia Progression through Lowering Inflammation in Retinal Pigment Epithelial Cell. Mediators Inflamm. 2021,2021:6660640. doi: 10.1155/2021/6660640
    Read this paper
  • Lho Y, Do JY, Heo JY, et al. Effects of TGF-β1 Receptor Inhibitor GW788388 on the Epithelial to Mesenchymal Transition of Peritoneal Mesothelial Cells. Int J Mol Sci. 2021,22(9). doi: 10.3390/ijms22094739
    Read this paper
  • Zhang M, Zhu P, Wang Y, et al. Bilateral sympathetic stellate ganglionectomy attenuates myocardial remodelling and fibrosis in a rat model of chronic volume overload. J Cell Mol Med. 2019,23(2):1001-1013. doi: 10.1111/jcmm.14000
    Read this paper
  • Wei CC, Kung YJ, Chen CS, et al. Allergic Conjunctivitis-induced Retinal Inflammation Promotes Myopia Progression. EBioMedicine. 2018,28:274-286. doi: 10.1016/j.ebiom.2018.01.024
    Read this paper
  • Wong K, Trudel G, Laneuville O. Intra-articular collagenase injection increases range of motion in a rat knee flexion contracture model. Drug Des Devel Ther. 2018,12:15-24. doi: 10.2147/DDDT.S144602
    Read this paper
  • Schendel SA. Autologous Adipose-Derived Tissue Matrix Part I: Biologic Characteristics. Aesthet Surg J. 2017,37(9):1062-1068. doi: 10.1093/asj/sjx059
    Read this paper