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ProductsBack/Collagen IV antibody

Collagen IV antibody

Research Use Only
GTX19808
GeneTex
ApplicationsImmunoFluorescence, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin, RadioImmunoAssay
DownloadDatasheet
Product group Antibodies
ReactivityMouse
TargetCOL4A1
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Overview

  • Supplier
    GeneTex
  • Product Name
    Collagen IV antibody
  • Delivery Days Customer
    9
  • Antibody Specificity
    Recognises Mouse Collagen Type IV (100% by RIA). Does not react with Mouse Collagen Types I or III, Human Collagen Type IV or V, Mouse Fibronectin or Mouse Laminin (<0.1% by RIA).,We do not recommend use of this product for Human.
  • Application Supplier Note
    ELISA: 1/200. IF: 1/80. Use on frozen mouse tissues (skin, liver). IHC-P: 1/500. RIA: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the end user.
  • Applications
    ImmunoFluorescence, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin, RadioImmunoAssay
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    3 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID1282
  • Target name
    COL4A1
  • Target description
    collagen type IV alpha 1 chain
  • Target synonyms
    arresten; BSVD; BSVD1; COL4A1 NC1 domain; COL4A1s; collagen alpha-1(IV) chain; collagen IV, alpha-1 polypeptide; collagen of basement membrane, alpha-1 chain; PADMAL; RATOR
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    Collagen IV is a major constituent of the basement membranes along with laminins and enactins. It is composed of alpha 1 IV chain and alpha 2 IV chain in 2:1 ratio . It can form insoluble fibers with high tensile strength. Antibody to collagen IV is useful in detecting the loss of parts of basement membrane in carcinomas.
  • Reactivity
    Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Bone marrow sinusoidal endothelium controls terminal erythroid differentiation and reticulocyte maturation. Heil J et al., 2021 Nov 29, Nat Commun
    Read more
  • Imbalanced Activation of Wnt-/beta-Catenin-Signaling in Liver Endothelium Alters Normal Sinusoidal Differentiation. Koch PS et al., 2021, Front Physiol
    Read more