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CREB (phospho Ser133) antibody

GTX130379
GeneTex
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetCREB1
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Overview

  • Supplier
    GeneTex
  • Product Name
    CREB (phospho Ser133) antibody
  • Delivery Days Customer
    9
  • Antibody Specificity
    Based on the internal tests, this antibody can recognize human CREB phosphorylated at Ser133 and human ATF1 phosphorylated at Ser63 due to sequence homology.This antibody is raised against human CREB phosphorylated at Ser133, and it also may detect the ph
  • Application Supplier Note
    WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.34 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID1385
  • Target name
    CREB1
  • Target description
    cAMP responsive element binding protein 1
  • Target synonyms
    active transcription factor CREB; cAMP-response element-binding protein-1; CREB; CREB-1; cyclic adenosine 3',5'-monophosphate response element binding protein; cyclic adenosine 3',5'-monophosphate response element-binding protein CREB; cyclic AMP-responsive element-binding protein 1; transactivator protein
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP16220
  • Protein Name
    Cyclic AMP-responsive element-binding protein 1
  • Scientific Description
    This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Repositioning VU-0365114 as a novel microtubule-destabilizing agent for treating cancer and overcoming drug resistance.
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  • Hyperforin Elicits Cytostatic/Cytotoxic Activity in Human Melanoma Cell Lines, Inhibiting Pro-Survival NF-kappaB, STAT3, AP1 Transcription Factors and the Expression of Functional Proteins Involved in Mitochondrial and Cytosolic Metabolism.
    Read more
  • 3,5-Dicaffeoylquinic Acid Lowers 3T3-L1 Mitotic Clonal Expansion and Adipocyte Differentiation by Enhancing Heme Oxygenase-1 Expression. Raineri A et al., 2021 Aug 19, Molecules
    Read more
  • The neuroprotective effects of SIRT1 in mice carrying the APP/PS1 double-transgenic mutation and in SH-SY5Y cells over-expressing human APP670/671 may involve elevated levels of alpha7 nicotinic acetylcholine receptors. Cao K et al., 2020 Jan 30, Aging (Albany NY)
    Read more