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Insulin antibody [E2E3]

Name: Insulin antibody [E2E3]
SKU: GTX73558_G10
Availability: BackOrder

GTX73558

ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

TargetINS

Overview

Supplier
GeneTex
Product Name
Insulin antibody [E2E3]
Delivery Days Customer
9
Applications
ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Monoclonal
Clone ID
E2E3
Conjugate
Unconjugated
Gene ID3630
Target name
INS
Target description
insulin
Target synonyms
IDDM, IDDM1, IDDM2, ILPR, IRDN, MODY10, PNDM4, insulin, preproinsulin, proinsulin
Host
Mouse
Isotype
IgG1
Protein IDP01308
Protein Name
Insulin
Scientific Description
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5 region and with the IGF2 gene at the 3 region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
Storage Instruction
2°C to 8°C
UNSPSC
12352203

O'Brien K, Bhatia A, Tsen F, et al. Identification of the critical therapeutic entity in secreted Hsp90α that promotes wound healing in newly re-standardized healthy and diabetic pig models. PLoS One. 2014,9(12):e113956. doi: 10.1371/journal.pone.0113956
Read this paper