CYP17A1 antibody [N3C2], Internal
GTX113670
Overview
- SupplierGeneTex
- Product NameCYP17A1 antibody [N3C2], Internal
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.81 mg/ml
- ConjugateUnconjugated
- Gene ID1586
- Target nameCYP17A1
- Target descriptioncytochrome P450 family 17 subfamily A member 1
- Target synonyms17-alpha-hydroxyprogesterone aldolase; CPT7; CYP17; CYPXVII; cytochrome P450 17A1; cytochrome p450 XVIIA1; cytochrome P450, family 17, subfamily A, polypeptide 1; cytochrome P450, subfamily XVII (steroid 17-alpha-hydroxylase), adrenal hyperplasia; cytochrome P450c17; cytochrome P450-C17; P450C17; S17AH; steroid 17-alpha-hydroxylase/17,20 lyase; steroid 17-alpha-monooxygenase
- HostRabbit
- IsotypeIgG
- Protein IDP05093
- Protein NameSteroid 17-alpha-hydroxylase/17,20 lyase
- Scientific DescriptionThis gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia. [provided by RefSeq]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Assessment of the potential of polyphenols as a CYP17 inhibitor free of adverse corticosteroid elevation. Lin CJ et al., 2014 Aug 1, Biochem PharmacolRead more