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CYP17A1 antibody [N3C2], Internal

GTX113670
GeneTex
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetCYP17A1
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Overview

  • Supplier
    GeneTex
  • Product Name
    CYP17A1 antibody [N3C2], Internal
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.81 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID1586
  • Target name
    CYP17A1
  • Target description
    cytochrome P450 family 17 subfamily A member 1
  • Target synonyms
    17-alpha-hydroxyprogesterone aldolase; CPT7; CYP17; CYPXVII; cytochrome P450 17A1; cytochrome p450 XVIIA1; cytochrome P450, family 17, subfamily A, polypeptide 1; cytochrome P450, subfamily XVII (steroid 17-alpha-hydroxylase), adrenal hyperplasia; cytochrome P450c17; cytochrome P450-C17; P450C17; S17AH; steroid 17-alpha-hydroxylase/17,20 lyase; steroid 17-alpha-monooxygenase
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP05093
  • Protein Name
    Steroid 17-alpha-hydroxylase/17,20 lyase
  • Scientific Description
    This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia. [provided by RefSeq]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Assessment of the potential of polyphenols as a CYP17 inhibitor free of adverse corticosteroid elevation. Lin CJ et al., 2014 Aug 1, Biochem Pharmacol
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