Cytostatin [457070-06-3]

AdipoGen Life Sciences

Cytostatin

10

457070-06-3

Research Use Only

>75%

Warning

C21H32NaO7P

450.4

Chemical. CAS: 457070-06-3 - 682329-63-1 (free base). Formula: C21H32NaO7P. MW: 450.4. Isolated from Streptomyces sp. MJ654-NF4. Potent and selective protein phosphatase 2A (PP2A) inhibitor. Cell adhesion inhibitor. Inhibits the adhesion of B16 melanoma cells to laminin and collagen type IV in a dose dependent manner but not to fibronectin. Antitumor agent. Antimetastatic. Apoptosis inducer. - Potent and selective protein phosphatase 2A (PP2A) inhibitor [4-7]. Cell adhesion inhibitor [1]. Inhibits the adhesion of B16 melanoma cells to laminin and collagen type IV in a dose dependent manner but not to fibronectin [2]. Antitumor agent. Antimetastatic [2, 7]. Apoptosis inducer [3].

[Na+].C\C=C\C=C/C=C\C(O)C(C)C(CCC(C)C1OC(=O)C=CC1C)OP(O)([O-])=O

-20°C,2°C to 8°C

12352200