DCK antibody
GTX102800
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetDCK
Overview
- SupplierGeneTex
- Product NameDCK antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:1000-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.41 mg/ml
- ConjugateUnconjugated
- Gene ID1633
- Target nameDCK
- Target descriptiondeoxycytidine kinase
- Target synonymsdeoxyadenosine kinase; deoxycytidine kinase; deoxyguanosine kinase; deoxynucleoside kinase
- HostRabbit
- IsotypeIgG
- Protein IDP27707
- Protein NameDeoxycytidine kinase
- Scientific DescriptionDeoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- In vitro and molecular chemosensitivity in human cholangiocarcinoma tissues. Suksawat M et al., 2019, PLoS OneRead more
- Genome-scale CRISPR/Cas9 screen determines factors modulating sensitivity to ProTide NUC-1031. Sarr A et al., 2019 May 21, Sci RepRead more
- Using genome-wide CRISPR library screening with library resistant DCK to find new sources of Ara-C drug resistance in AML. Kurata M et al., 2016 Nov 3, Sci RepRead more
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