More than 130 suppliers
ISO certified
In-house tech support
we Connect you
Bio-Connect
ProductsBack/DCK antibody

DCK antibody

GTX102800
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
TargetDCK
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request
More than 130 suppliers
ISO certified
In-house tech support

Overview

  • Supplier
    GeneTex
  • Product Name
    DCK antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:1000-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.41 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID1633
  • Target name
    DCK
  • Target description
    deoxycytidine kinase
  • Target synonyms
    deoxyadenosine kinase; deoxycytidine kinase; deoxyguanosine kinase; deoxynucleoside kinase
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP27707
  • Protein Name
    Deoxycytidine kinase
  • Scientific Description
    Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • In vitro and molecular chemosensitivity in human cholangiocarcinoma tissues. Suksawat M et al., 2019, PLoS One
    Read more
  • Genome-scale CRISPR/Cas9 screen determines factors modulating sensitivity to ProTide NUC-1031. Sarr A et al., 2019 May 21, Sci Rep
    Read more
  • Using genome-wide CRISPR library screening with library resistant DCK to find new sources of Ara-C drug resistance in AML. Kurata M et al., 2016 Nov 3, Sci Rep
    Read more

Related products

Product group Antibodies
RayBiotech
Anti-DCK Antibody144-01794
ApplicationsImmunoFluorescence, Western Blot, ImmunoHistoChemistry
TargetDCK
  • SizePrice
Product group Antibodies
Bethyl Laboratories
Rabbit anti-DCK Antibody, Affinity PurifiedA304-266A
ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry
TargetDCK
  • SizePrice
WB analysis of various sample lysates using GTX32553 DCK antibody. Dilution : 1:1000 Loading : 25microg per lane
Product group Antibodies
GeneTex
DCK antibodyGTX32553
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
TargetDCK
  • SizePrice
Product group Antibodies
Assay Genie
IRE1 AntibodyCAB17940
TargetDCK
  • SizePrice
Product group Antibodies
LifeSpan BioSciences
DCK / Deoxycytidine kinase AntibodyLS-C404679
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
TargetDCK
  • SizePrice
Immunohistochemistry of paraffin-embedded human glioma using CSB-PA006547LA01HU at dilution of 1:100
Product group Antibodies
Cusabio
DCK AntibodyCSB-PA006547LA01HU
ApplicationsELISA, ImmunoHistoChemistry
ReactivityHuman
TargetDCK
  • SizePrice
Immunofluorescent staining of human cell line MCF7 shows localization to nucleus.
Product group Antibodies
Atlas Antibodies
Anti-DCK AntibodyHPA059609
ApplicationsImmunoCytoChemistry
ReactivityHuman
TargetDCK
  • SizePrice
Figure 1. Western blot analysis of DCK using anti-DCK antibody (A01655-1). Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each lane was loaded with 30 ug of sample under reducing conditions. Lane 1: human Jurkat whole cell lysates, Lane 2: rat thymus tissue lysates, Lane 3: mouse thymus tissue lysates. After electrophoresis, proteins were transferred to a nitrocellulose membrane at 150 mA for 50-90 minutes. Blocked the membrane with 5% non-fat milk/TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-DCK antigen affinity purified polyclonal antibody (Catalog # A01655-1) at 0.5 microg/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:5000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for DCK at approximately 31 kDa. The expected band size for DCK is at 31 kDa.
Product group Antibodies
Boster Bio
Anti-DCK Antibody Picoband(r)A01655-1-CARRIER-FREE
ApplicationsFlow Cytometry, Western Blot, ELISA, ImmunoHistoChemistry
TargetDCK
  • SizePrice
Product group Antibodies
References
GeneTex
DCK antibody [GT7710]GTX632062
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
TargetDCK
  • SizePrice
Product group Antibodies
References
GeneTex
DCK antibody [GT10412]GTX632065
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
TargetDCK
  • SizePrice