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WB analysis of MCF-7 whole cell lysate using GTX25508 DDR1 antibody. Loading : 20 microg per lane Dilution : 1:2000
WB analysis of MCF-7 whole cell lysate using GTX25508 DDR1 antibody. Loading : 20 microg per lane Dilution : 1:2000
WB analysis of MCF-7 whole cell lysate using GTX25508 DDR1 antibody. Loading : 20 microg per lane Dilution : 1:2000

DDR1 antibody

GTX25508
GeneTex
ApplicationsFlow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetDDR1
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Overview

  • Supplier
    GeneTex
  • Product Name
    DDR1 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:1000. IHC-P: 1:10-1:50. FACS: 1:25. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID780
  • Target name
    DDR1
  • Target description
    discoidin domain receptor tyrosine kinase 1
  • Target synonyms
    CAK, CD167, DDR, EDDR1, HGK2, MCK10, NEP, NTRK4, PTK3, PTK3A, RTK6, TRKE, epithelial discoidin domain-containing receptor 1, CD167 antigen-like family member A, PTK3A protein tyrosine kinase 3A, cell adhesion kinase, mammary carcinoma kinase 10, neuroepithelial tyrosine kinase, neurotrophic tyrosine kinase, receptor, type 4, protein-tyrosine kinase RTK-6, tyrosine kinase DDR, tyrosine-protein kinase CAK
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ08345
  • Protein Name
    Epithelial discoidin domain-containing receptor 1
  • Scientific Description
    Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Inhibition of DDR1 reduces invasive features of human A375 melanoma, HT29 colon carcinoma and SK-HEP hepatoma cells. Romayor I et al., 2020 Dec, Cell Adh Migr
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