Diablo antibody

GeneTex

Diablo antibody

9

C terminus of the human DIABLO protein.

For WB: Use at a dilution of 1:500-1:1,000. Optimal dilutions/concentrations should be determined by the researcher.

Western Blot

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

Liquid

DIABLO

diablo IAP-binding mitochondrial protein

DFNA64; diablo homolog, mitochondrial; diablo-like protein; direct IAP-binding protein with low pI; second mitochondria-derived activator of caspase; SMAC

Rabbit

IgG

Diablo homolog, mitochondrial

This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]

Human

-20°C or -80°C,2°C to 8°C

12352203