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Diablo antibody

Research Use Only
GTX70448
GeneTex
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetDIABLO
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Overview

  • Supplier
    GeneTex
  • Product Name
    Diablo antibody
  • Delivery Days Customer
    9
  • Antibody Specificity
    C terminus of the human DIABLO protein.
  • Application Supplier Note
    For WB: Use at a dilution of 1:500-1:1,000. Optimal dilutions/concentrations should be determined by the researcher.
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID56616
  • Target name
    DIABLO
  • Target description
    diablo IAP-binding mitochondrial protein
  • Target synonyms
    DFNA64; diablo homolog, mitochondrial; diablo-like protein; direct IAP-binding protein with low pI; second mitochondria-derived activator of caspase; SMAC
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9NR28
  • Protein Name
    Diablo homolog, mitochondrial
  • Scientific Description
    This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203