DLGAP1 antibody

GeneTex

DLGAP1 antibody

9

WB: 0.5 - 1 microg/mL. IHC-P: 5 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

DLGAP1

DLG associated protein 1

DAP1; DAP-1; DAP-1-ALPHA; DAP-1-BETA; discs large homolog associated protein 1; disks large-associated protein 1; DLGAP1A; DLGAP1B; GKAP; guanylate kinase-associated protein; PSD-95/SAP90 binding protein 1; SAP90/PSD-95-associated protein 1; SAPAP1

Rabbit

IgG

Disks large-associated protein 1

SAP90/PSD-95-associated protein 1 (SAPAP1, also known as DLGAP1 or GKAP) is a member of a protein family whose members specifically interact with PSD-95/SAP90, a membrane-associated guanylate kinase localized at postsynaptic density (PSD) in neuronal cells. Like the other SAPAP proteins, SAPAP1 is thought to be an adaptor protein that also interacts with different synaptic scaffolding proteins, cytoskeletal and signaling components, such as focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2). SAPAP1 mRNA is targeted to cell bodies in a similar manner to SAPAP2 and -4, whereas SAPAP3 mRNA is detected mainly in cell bodies. SAPAP1 protein however, is targeted to the synapse and is not reliant on the synaptic localization of PSD-95 or the synaptic scaffolding molecule (S-SCAM). At least three isoforms of SAPAP1 are known to exist. This SAPAP1 antibody will not cross-react with other SAPAP proteins.

-20°C or -80°C,2°C to 8°C

12352203