eIF2 alpha antibody [3H7] - Overexpression Validated

GeneTex

eIF2 alpha antibody [3H7] - Overexpression Validated

10

Flow Cytometry, Western Blot

Research Use Only

Monoclonal

3H7

0.62 mg/ml

Mouse

IgG

Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.

Canine, Human, Monkey, Rat

2°C to 8°C,-20°C

12352203