eIF2 alpha antibody [3H7]

GeneTex

eIF2 alpha antibody [3H7]

9

WB: 1:2000. FCM: 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Flow Cytometry, Western Blot

Research Use Only

Monoclonal

3H7

0.62 mg/ml

Unconjugated

EIF2S1

eukaryotic translation initiation factor 2 subunit alpha

EIF-2, EIF-2A, EIF-2alpha, EIF2, EIF2A, eukaryotic translation initiation factor 2 subunit 1, eIF-2-alpha, eIF2-alpha, eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa

Mouse

IgG1

Eukaryotic translation initiation factor 2 subunit 1

Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.

Canine, Human, Monkey, Rat

-20°C or -80°C,2°C to 8°C

41116161