Endothelin A receptor antibody
GTX71455
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetEDNRA
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Overview
- SupplierGeneTex
- Product NameEndothelin A receptor antibody
- Delivery Days Customer9
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID1909
- Target nameEDNRA
- Target descriptionendothelin receptor type A
- Target synonymsendothelin receptor subtype A; endothelin-1 receptor; endothelin-1-specific receptor; ETA; ET-A; ETAR; ETA-R; ETRA; G protein-coupled receptor; hET-AR; MFDA
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
- ReactivityHuman
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203
References
- BMPR2 mutation alters the lung macrophage endothelin-1 cascade in a mouse model and patients with heritable pulmonary artery hypertension. Talati M et al., 2010 Sep, Am J Physiol Lung Cell Mol PhysiolRead more
- Increased tissue endothelin-1 and endothelin-B receptor expression in temporal arteries from patients with giant cell arteritis. Dimitrijevic I et al., 2010 Mar, OphthalmologyRead more