EP300 antibody [RW128]

GeneTex

EP300 antibody [RW128]

7

WB: 1:250 - 1:500. ICC/IF: 1:10 - 1:2000. FACS: 1 microg/ml. IP: 1:10 - 1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry

Research Use Only

Monoclonal

RW128

1 mg/ml

Unconjugated

EP300

EP300 lysine acetyltransferase

KAT3B, MKHK2, RSTS2, p300, histone acetyltransferase p300, E1A binding protein p300, E1A-associated protein p300, E1A-binding protein, 300kD, histone butyryltransferase p300, histone crotonyltransferase p300, p300 HAT, protein 2-hydroxyisobutyryltransferase p300, protein lactyltransferas p300, protein propionyltransferase p300

Mouse

IgG1

Histone acetyltransferase p300

This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq]

-20°C or -80°C,2°C to 8°C

12352203