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Western Blot analysis of HepG2 cells using FAK Polyclonal Antibody at dilution of 1:500.
Western Blot analysis of HepG2 cells using FAK Polyclonal Antibody at dilution of 1:500.
Western Blot analysis of HepG2 cells using FAK Polyclonal Antibody at dilution of 1:500.

FAK Polyclonal Antibody

Research Use Only
E-AB-31399
Elabscience
Product group Antibodies
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More than 130 suppliers
ISO certified
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Overview

  • Supplier
    Elabscience
  • Product Name
    FAK Polyclonal Antibody
  • Delivery Days Customer
    12
  • Applications Supplier
    WB,IHC,IF,ELISA
  • Certification
    Research Use Only
  • Concentration
    1 mg/ml
  • Scientific Description
    Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Microtubule-induced dephosphorylation at Tyr-397 is crucial for the induction of focal adhesion disassembly. Plays a potential role in oncogenic transformations resulting in increased kinase activity.
  • UNSPSC
    12352203