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Sample (30 ug of whole cell lysate) A:NIH-3T3 10% SDS PAGE GTX101807 diluted at 1:1000
Sample (30 ug of whole cell lysate) A:NIH-3T3 10% SDS PAGE GTX101807 diluted at 1:1000
Sample (30 ug of whole cell lysate) A:NIH-3T3 10% SDS PAGE GTX101807 diluted at 1:1000

Fibrillarin antibody

GTX101807
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetFBL
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Overview

  • Supplier
    GeneTex
  • Product Name
    Fibrillarin antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID2091
  • Target name
    FBL
  • Target description
    fibrillarin
  • Target synonyms
    FIB, FLRN, Nop1, RNU3IP1, rRNA 2'-O-methyltransferase fibrillarin, 34 kDa nucleolar scleroderma antigen, 34-kD nucleolar scleroderma antigen, RNA, U3 small nucleolar interacting protein 1, U6 snRNA 2'-O-methyltransferase fibrillarin, histone-glutamine methyltransferase
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP22087
  • Protein Name
    rRNA 2'-O-methyltransferase fibrillarin
  • Scientific Description
    This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8% of humans with the autoimmune disease scleroderma recognize fibrillarin. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Bogard B, Francastel C, Hubé F. Systematic Identification and Functional Validation of New snoRNAs in Human Muscle Progenitors. Noncoding RNA. 2021,7(3). doi: 10.3390/ncrna7030056
    Read this paper
  • Sikorski K, Mehta A, Inngjerdingen M, et al. A high-throughput pipeline for validation of antibodies. Nat Methods. 2018,15(11):909-912. doi: 10.1038/s41592-018-0179-8
    Read this paper

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