FLIP antibody [N1C1]
GTX113047
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetCFLAR
Overview
- SupplierGeneTex
- Product NameFLIP antibody [N1C1]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID8837
- Target nameCFLAR
- Target descriptionCASP8 and FADD like apoptosis regulator
- Target synonymsCASH; CASP8 and FADD-like apoptosis regulator; CASP8AP1; caspase homolog; caspase-eight-related protein; caspase-like apoptosis regulatory protein; caspase-related inducer of apoptosis; Casper; cellular FLICE-like inhibitory protein; cFLIP; c-FLIP; c-FLIPL; c-FLIPR; c-FLIPS; CLARP; FADD-like antiapoptotic molecule 1; FLAME; FLAME1; FLAME-1; FLIP; I-FLICE; inhibitor of FLICE; MACH-related inducer of toxicity; MRIT; testis secretory sperm-binding protein Li 233m; usurpin beta
- HostRabbit
- IsotypeIgG
- Protein IDO15519
- Protein NameCASP8 and FADD-like apoptosis regulator
- Scientific DescriptionApoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells. Acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. Lacks enzymatic (caspase) activity.
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Pulmonary Delivery of Extracellular Vesicle-Encapsulated Dinaciclib as an Effective Lung Cancer Therapy.Read more