Frizzled 7 antibody
GTX71555
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Human, Mammals
TargetFZD7
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Overview
- SupplierGeneTex
- Product NameFrizzled 7 antibody
- Delivery Days Customer9
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID8324
- Target nameFZD7
- Target descriptionfrizzled class receptor 7
- Target synonymsfrizzled 7, seven transmembrane spanning receptor; frizzled family receptor 7; frizzled homolog 7; Frizzled, drosophila, homolog of, 7; frizzled-7; fz-7; FzE3; hFz7
- HostRabbit
- IsotypeIgG
- Scientific DescriptionMembers of the frizzled gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. [provided by RefSeq, Jul 2008]
- ReactivityBovine, Human, Mammals
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203