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Galectin 3 antibody [B2C10]

GTX54467
GeneTex
ApplicationsFlow Cytometry, Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Neutralisation/Blocking
Product group Antibodies
ReactivityHuman, Mouse
TargetLGALS3
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Overview

  • Supplier
    GeneTex
  • Product Name
    Galectin 3 antibody [B2C10]
  • Delivery Days Customer
    9
  • Antibody Specificity
    The epitope of the monoclonal antibody B2C10 is found within the first 45 amino acids of galectin-3. The antibody B2C10 does not react with Galecin-3C.
  • Application Supplier Note
    *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry, Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Neutralisation/Blocking
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    B2C10
  • Concentration
    100 ug/ml
  • Conjugate
    Unconjugated
  • Gene ID3958
  • Target name
    LGALS3
  • Target description
    galectin 3
  • Target synonyms
    35 kDa lectin; advanced glycation end-product receptor 3; carbohydrate-binding protein 35; CBP35; epididymis secretory sperm binding protein; GAL3; galactose-specific lectin 3; GALBP; galectin-3; GALIG; IgE-binding protein; L31; laminin-binding protein; lectin L-29; lectin, galactoside-binding, soluble, 3; LGALS2; MAC2; MAC-2 antigen
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP17931
  • Protein Name
    Galectin-3
  • Scientific Description
    This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2014]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Human galectin-3 is a novel chemoattractant for monocytes and macrophages. Sano H et al., 2000 Aug 15, J Immunol
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  • Modulation of functional properties of galectin-3 by monoclonal antibodies binding to the non-lectin domains. Liu FT et al., 1996 May 14, Biochemistry
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