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ICC/IF analysis of NIH3T3 cells using GTX11317 gamma Tubulin antibody at 1:500 (green).Actin staining with phalloidin rhodamine conjugate(red). Nuclear staining with DAPI(blue).
ICC/IF analysis of NIH3T3 cells using GTX11317 gamma Tubulin antibody at 1:500 (green).Actin staining with phalloidin rhodamine conjugate(red). Nuclear staining with DAPI(blue).
ICC/IF analysis of NIH3T3 cells using GTX11317 gamma Tubulin antibody at 1:500 (green).Actin staining with phalloidin rhodamine conjugate(red). Nuclear staining with DAPI(blue).

gamma Tubulin antibody

GTX11317
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
TargetTUBG1
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Overview

  • Supplier
    GeneTex
  • Product Name
    gamma Tubulin antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:1,000. ICC/IF: 1:5,000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID7283
  • Target name
    TUBG1
  • Target description
    tubulin gamma 1
  • Target synonyms
    CDCBM4; gamma-tubulin complex component 1; GCP-1; TUBG; TUBGCP1; tubulin gamma-1 chain; tubulin, gamma polypeptide
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP23258
  • Protein Name
    Tubulin gamma-1 chain
  • Scientific Description
    The protein that binds microtubule minus ends and is responsible for mediating the link between microtubules and the centrosome is called gamma tubulin. Gamma Tubulin functions as the microtubule nucleator at the microtubule organizing centre (MTOC). By binding to the beta tubulin half of the tubulin molecule, it establishes the polarity of a microtubule, leaving the alpha tubulin half exposed at the positive end. Gamma Tubulin (approx. 48 kD) is a ubiquitous and highly conserved protein within the MTOCs in eukaryotic kingdom. It is related to alpha and beta tubulin and is, thus, a member of the tubulin superfamily of proteins. However, its abundance is less than 1% of the level of either alpha or beta tubulin. Moreover, unlike alpha and beta tubulin, it is not a component of microtubules. Rather, it is located at the MTOC. gamma Tubulin shares approximately 28-32% identity with alpha tubulin from various organisms and 32-36% identity with beta tubulins. The detection, localization and characterization of proteins involved in microtubule function is fundamental to the understanding of mitosis, meiosis and the microtubule cytoskeleton. Antibodies reacting specifically with gamma tubulin serve as an essential tool in the detection of the presence and role of this molecule in various cellular settings.
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

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