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ProductsBack/gamma Tubulin antibody

gamma Tubulin antibody

GTX113286
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse, Rat, Zebra Fish
TargetTUBG1
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Overview

  • Supplier
    GeneTex
  • Product Name
    gamma Tubulin antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.24 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID7283
  • Target name
    TUBG1
  • Target description
    tubulin gamma 1
  • Target synonyms
    CDCBM4; gamma-tubulin complex component 1; GCP-1; TUBG; TUBGCP1; tubulin gamma-1 chain; tubulin, gamma polypeptide
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    This gene encodes a member of the tubulin superfamily. The encoded protein localizes to the centrosome where it binds to microtubules as part of a complex referred to as the gamma-tubulin ring complex. The protein mediates microtubule nucleation and is required for microtubule formation and progression of the cell cycle. A pseudogene of this gene is found on chromosome 7. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat, Zebra Fish
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Bi-allelic variants in CEP295 cause Seckel-like syndrome presenting with primary microcephaly, developmental delay, intellectual disability, short stature, craniofacial and digital abnormalities.
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  • The non-canonical Wnt receptor Ror2 is required for cartilage cell polarity and morphogenesis of the craniofacial skeleton in zebrafish.
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  • CCHCR1-astrin interaction promotes centriole duplication through recruitment of CEP72. Ying Z et al., 2022 Oct 24, BMC Biol
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  • Slit-Robo signalling establishes a Sphingosine-1-phosphate gradient to polarise fin mesenchyme.
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  • Cilia proteins are biomarkers of altered flow in the vasculature. Gupta A et al., 2022 Mar 22, JCI Insight
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  • Type-3 Hyaluronan Synthase Attenuates Tumor Cells Invasion in Human Mammary Parenchymal Tissues. Lee WJ et al., 2021 Oct 29, Molecules
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  • Mutations in KIF7 implicated in idiopathic scoliosis in humans and axial curvatures in zebrafish. Terhune EA et al., 2021 Apr, Hum Mutat
    Read more
  • Ca2+ Release by IP3 Receptors Is Required to Orient the Mitotic Spindle. Lagos-Cabre R et al., 2020 Dec 15, Cell Rep
    Read more
  • A truncating mutation in the autophagy gene UVRAG drives inflammation and tumorigenesis in mice. Quach C et al., 2019 Dec 12, Nat Commun
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  • Cellular responses to ionizing radiation change quickly over time during early development in zebrafish. Honjo Y et al., 2019 May, Cell Biol Int
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