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ProductsBack/GCLC antibody [N1N3]

GCLC antibody [N1N3]

GTX113197
GeneTex
ApplicationsWestern Blot
DownloadDatasheet
Product group Antibodies
TargetGCLC
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Overview

  • Supplier
    GeneTex
  • Product Name
    GCLC antibody [N1N3]
  • Delivery Days Customer
    9
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID2729
  • Target name
    GCLC
  • Target description
    glutamate-cysteine ligase catalytic subunit
  • Target synonyms
    gamma-ECS; gamma-glutamylcysteine synthetase; GCL; GCS; GCS heavy chain; GLCL; GLCLC; glutamate--cysteine ligase catalytic subunit
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP48506
  • Protein Name
    Glutamate--cysteine ligase catalytic subunit
  • Scientific Description
    Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. The gene encoding the catalytic subunit encodes a protein of 367 amino acids with a calculated molecular weight of 72.773 kDa and maps to chromosome 6. The regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Deficiency of gamma-glutamylcysteine synthetase in human is associated with enzymopathic hemolytic anemia. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Sesamin Enhances Nrf2-Mediated Protective Defense against Oxidative Stress and Inflammation in Colitis via AKT and ERK Activation. Bai X et al., 2019, Oxid Med Cell Longev
    Read more
  • H2O2 induces caveolin-1 degradation and impaired mitochondrial function in E11 podocytes. Chen YH et al., 2017 Nov, Mol Med Rep
    Read more

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