GCLC antibody [N1N3]

GeneTex

GCLC antibody [N1N3]

9

Western Blot

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

GCLC

glutamate-cysteine ligase catalytic subunit

CNSHA7, GCL, GCS, GLCL, GLCLC, glutamate--cysteine ligase catalytic subunit, GCS heavy chain, gamma-ECS, gamma-glutamylcysteine synthetase

Rabbit

IgG

Glutamate--cysteine ligase catalytic subunit

Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. The gene encoding the catalytic subunit encodes a protein of 367 amino acids with a calculated molecular weight of 72.773 kDa and maps to chromosome 6. The regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Deficiency of gamma-glutamylcysteine synthetase in human is associated with enzymopathic hemolytic anemia. [provided by RefSeq]

-20°C or -80°C,2°C to 8°C

12352203