WB analysis of various sample lysates using GTX66057 GCLC antibody. Dilution : 1:3000 Loading : 25microg per lane
WB analysis of various sample lysates using GTX66057 GCLC antibody. Dilution : 1:3000 Loading : 25microg per lane
GCLC antibody
GTX66057
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetGCLC
Overview
- SupplierGeneTex
- Product NameGCLC antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500 - 1:3000. ICC/IF: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID2729
- Target nameGCLC
- Target descriptionglutamate-cysteine ligase catalytic subunit
- Target synonymsgamma-ECS; gamma-glutamylcysteine synthetase; GCL; GCS; GCS heavy chain; GLCL; GLCLC; glutamate--cysteine ligase catalytic subunit
- HostRabbit
- IsotypeIgG
- Protein IDP48506
- Protein NameGlutamate--cysteine ligase catalytic subunit
- Scientific DescriptionGlutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.[provided by RefSeq, Oct 2010]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203