WB analysis of various sample lysates using GTX33218 Geminin antibody. Dilution : 1:1000 Loading : 25microg per lane
WB analysis of various sample lysates using GTX33218 Geminin antibody. Dilution : 1:1000 Loading : 25microg per lane
Geminin antibody
GTX33218
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetGMNN
Overview
- SupplierGeneTex
- Product NameGeminin antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500 - 1:2000. IHC-P: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID51053
- Target nameGMNN
- Target descriptiongeminin DNA replication inhibitor
- Target synonymsGem; geminin; MGORS6
- HostRabbit
- IsotypeIgG
- Protein IDO75496
- Protein NameGeminin
- Scientific DescriptionThis gene encodes a protein that plays a critical role in cell cycle regulation. The encoded protein inhibits DNA replication by binding to DNA replication factor Cdt1, preventing the incorporation of minichromosome maintenance proteins into the pre-replication complex. The encoded protein is expressed during the S and G2 phases of the cell cycle and is degraded by the anaphase-promoting complex during the metaphase-anaphase transition. Increased expression of this gene may play a role in several malignancies including colon, rectal and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and two pseudogenes of this gene are located on the short arm of chromosome 16. [provided by RefSeq, Oct 2011]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203