
IHC-P analysis of human brain tissue using GTX87941 Girdin antibody. The picture on the right is blocked with the synthesized peptide.
Girdin antibody
GTX87941
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetCCDC88A
Overview
- SupplierGeneTex
- Product NameGirdin antibody
- Delivery Days Customer9
- Application Supplier NoteIHC-P: 1:50~1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID55704
- Target nameCCDC88A
- Target descriptioncoiled-coil domain containing 88A
- Target synonymsAKT-phosphorylation enhancer; APE; g alpha-interacting vesicle-associated protein; girders of actin filaments; girdin; GIV; GRDN; HkRP1; Hook-related protein 1; KIAA1212; PEHO; PEHOL
- HostRabbit
- IsotypeIgG
- Protein IDQ3V6T2
- Protein NameGirdin
- Scientific DescriptionThis gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203