GRK2 antibody

GeneTex

GRK2 antibody

9

WB: 1:500-1:3000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoPrecipitation, Western Blot

Research Use Only

Polyclonal

0.21 mg/ml

Unconjugated

GRK2

G protein-coupled receptor kinase 2

ADRBK1; adrenergic beta receptor kinase 1; BARK1; beta-adrenergic receptor kinase 1; BETA-ARK1; beta-ARK-1

Rabbit

IgG

Beta-adrenergic receptor kinase 1

The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq]

Human

-20°C or -80°C,2°C to 8°C

12352203