FACS analysis of A549 cells using GTX02538 Growth hormone Receptor antibody. Green : Primary antibody Blue : Secondary antibody only control Dilution : 1:20
Growth hormone Receptor antibody
GTX02538
ApplicationsFlow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mammals, Porcine, Rat, Sheep
TargetGHR
Overview
- SupplierGeneTex
- Product NameGrowth hormone Receptor antibody
- Delivery Days Customer9
- ApplicationsFlow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID2690
- Target nameGHR
- Target descriptiongrowth hormone receptor
- Target synonymsGH receptor; GHBP; GHIP; growth hormone binding protein; growth hormone receptor; mutant growth hormone receptor; serum binding protein; somatotropin receptor; truncated growth hormone receptor
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. In humans and rabbits, but not rodents, growth hormone binding protein (GHBP) is generated by proteolytic cleavage of the extracellular ligand-binding domain from the mature growth hormone receptor protein. Multiple alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jun 2011]
- ReactivityHuman, Mammals, Porcine, Rat, Sheep
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203