More than 130 suppliers
ISO certified
In-house tech support
we Connect you
Bio-Connect
ProductsBack/HDAC3 antibody

HDAC3 antibody

GTX113303
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse, Rat, Zebra Fish
TargetHDAC3
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request
More than 130 suppliers
ISO certified
In-house tech support

Overview

  • Supplier
    GeneTex
  • Product Name
    HDAC3 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.32 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID8841
  • Target name
    HDAC3
  • Target description
    histone deacetylase 3
  • Target synonyms
    HD3; histone deacetylase 3; KDAC3; RPD3; RPD3-2; SMAP45
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO15379
  • Protein Name
    Histone deacetylase 3
  • Scientific Description
    Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat, Zebra Fish
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Medulloblastoma uses GABA transaminase to survive in the cerebrospinal fluid microenvironment and promote leptomeningeal dissemination. Martirosian V et al., 2021 Jun 29, Cell Rep
    Read more
  • MicroRNA-148b Targets the TGF-beta Pathway to Regulate Angiogenesis and Endothelial-to-Mesenchymal Transition during Skin Wound Healing. Miscianinov V et al., 2018 Aug 1, Mol Ther
    Read more
  • An HDAC3-PROX1 corepressor module acts on HNF4alpha to control hepatic triglycerides. Armour SM et al., 2017 Sep 15, Nat Commun
    Read more
  • Histone deacetylase 3 prepares brown adipose tissue for acute thermogenic challenge. Emmett MJ et al., 2017 Jun 22, Nature
    Read more
  • In cortical neurons HDAC3 activity suppresses RD4-dependent SMRT export. Soriano FX et al., 2011, PLoS One
    Read more