WB analysis of extracts from mouse brain tissue using GTX55425 HDAC3 (phospho Ser424) antibody. Left : Primary antibody pre-incubated with the antigen specific peptide Right : Primary antibody
WB analysis of extracts from mouse brain tissue using GTX55425 HDAC3 (phospho Ser424) antibody. Left : Primary antibody pre-incubated with the antigen specific peptide Right : Primary antibody
HDAC3 (phospho Ser424) antibody
GTX55425
Overview
- SupplierGeneTex
- Product NameHDAC3 (phospho Ser424) antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID8841
- Target nameHDAC3
- Target descriptionhistone deacetylase 3
- Target synonymsHD3; histone deacetylase 3; KDAC3; RPD3; RPD3-2; SMAP45
- HostRabbit
- IsotypeIgG
- Protein IDO15379
- Protein NameHistone deacetylase 3
- Scientific DescriptionHistones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq, Jul 2008]
- ReactivityMouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203