Western blot analysis of extracts from HepG2 cells, using HDAC9 antibody.
Western blot analysis of extracts from HepG2 cells, using HDAC9 antibody.
HDAC9 Antibody
CSB-PA831141
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetHDAC9
Overview
- SupplierCusabio
- Product NameHDAC9 Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID9734
- Target nameHDAC9
- Target descriptionhistone deacetylase 9
- Target synonymsHD7; HD7b; HD9; HDAC; HDAC7; HDAC7B; HDAC9B; HDAC9FL; HDRP; histone deacetylase 4/5-related protein; histone deacetylase 7B; histone deacetylase 9; MEF-2 interacting transcription repressor (MITR) protein; MITR
- HostRabbit
- IsotypeIgG
- Protein IDQ9UKV0
- Protein NameHistone deacetylase 9
- Scientific DescriptionResponsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Represses MEF2-dependent transcription. Isoform 3 lacks active site residues and therefore is catalytically inactive. Represses MEF2-dependent transcription by recruiting HDAC1 and/or HDAC3. Seems to inhibit skeletal myogenesis and to be involved in heart development. Protects neurons from apoptosis, both by inhibiting JUN phosphorylation by MAPK10 and by repressing JUN transcription via HDAC1 recruitment to JUN promoter. Michael Haberland, Mol. Cell. Biol., Jan 2007; 27: 518 - 525. Xianbo Zhou, PNAS, Sep 2001; 98: 10572. Kevin Petrie, J. Biol. Chem., Apr 2003; 278: 16059 - 16072. Kevin Petrie, Blood (ASH Annual Meeting Abstracts), Nov 2004; 104: 1120.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203